Individualized dosage.
Adult Premed 50-100 mcg (1-2 mL) via IM 30-60 min prior to surgery.
Patient w/ spontaneous resp Initially 50-200 mcg w/ supplements of 50 mcg. Significant resp depression follow doses of >200 mcg.
Patient where ventilation is assisted Initially 300-3,500 mcg (up to 50 mcg/kg) w/ supplements of 100-200 mcg or higher depending on the response.
Adjunct to general anaesth Initial induction of 50-100 mcg (1-2 mL) via IV, repeat at 2-3 min intervals until desired effect is achieved.
Elderly & poor risk patient Reduce dose of 25-50 mcg (0.5-1 mL). Maintenance: 25-50 mcg (0.5-1 mL) IM/IV when movement &/or changes in vital signs indicate surgical stress or lightening of analgesia.
Adjunct to regional anaesth 50-100 mcg (1-2 mL) via IM for the control of pain, tachypnoea & emergence delirium. May be repeated in 1-2 hr as needed.
Post-op 50-100 mcg (1-2 mL) via IM for the control of pain, tachypnoea & emergence delirium. May be repeated in 1-2 hr as needed.
Childn 2-12 yr Induction & maintenance: Reduced dose of 20-30 mcg (0.4-0.6 mL) per 10 kg.
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